Electrophoresis Testing at IDC (ISO15189:2022 Accredited Laboratory) – Advanced Capillary Electrophoresis for Accurate Hemoglobin & Protein Analysis
Electrophoresis is an essential laboratory technique used to separate and identify proteins and hemoglobin variants, playing a critical role in the diagnosis of hematological disorders, hemoglobinopathies, monoclonal gammopathies, and other protein abnormalities. At Islamabad Diagnostic Centre (IDC), electrophoresis testing is performed using the Sebia CAPILLARYS OCTA, a fully automated capillary electrophoresis analyzer that provides high-resolution separation, excellent analytical performance, and standardized results. This advanced technology ensures precise identification and quantification of hemoglobin fractions and serum proteins, supporting accurate diagnosis and improved clinical decision-making.
Why IDC’s Electrophoresis Testing is Different
Performed on the Sebia CAPILLARYS OCTA, an advanced fully automated capillary electrophoresis system.
Capillary Electrophoresis (CE) is regarded as a reference (gold-standard) methodology for many electrophoretic applications due to its high analytical resolution, automation, and reproducibility.
Superior separation of hemoglobin fractions and serum protein components compared with conventional gel electrophoresis.
High analytical sensitivity enables detection of small abnormal fractions and monoclonal proteins.
Fully automated workflow minimizes manual handling and analytical variability.
Rapid turnaround time with standardized, reproducible results.
Expert interpretation by experienced pathologists using stringent quality assurance procedures.
Benefits of Capillary Electrophoresis
Excellent resolution for accurate separation of proteins and hemoglobin variants.
Improved detection of abnormal hemoglobin fractions including Hb S, Hb C, Hb D, Hb E, and elevated Hb F.
Accurate quantification of HbA₂, essential for diagnosing β-thalassemia trait.
Reliable identification of monoclonal proteins (M-proteins) in serum protein electrophoresis.
Enhanced diagnostic confidence through precise fraction separation and automated analysis.
Reduced analytical errors through standardized automated processing.
Clinical Applications
Hemoglobin Electrophoresis
β-Thalassemia Trait and β-Thalassemia Major
α-Thalassemia (as part of the diagnostic work-up)
Sickle Cell Disease and Sickle Cell Trait
Hemoglobin C, D, and E disorders
Hereditary Persistence of Fetal Hemoglobin (HPFH)
Unexplained anemia and abnormal red cell indices
Prenatal and family screening for hemoglobinopathies
Serum Protein Electrophoresis (SPEP)
Multiple Myeloma
Monoclonal Gammopathy of Undetermined Significance (MGUS)
Waldenström Macroglobulinemia
Plasma Cell Dyscrasias
Chronic inflammatory disorders
Liver diseases
Nephrotic syndrome
Immunodeficiency disorders
Protein-losing conditions
Why Choose IDC?
IDC is ISO15189:2022 accredited laboratory.
Advanced Sebia CAPILLARYS OCTA fully automated capillary electrophoresis platform.
High-resolution separation and precise quantification of hemoglobin and serum protein fractions.
Comprehensive testing for Hemoglobin Electrophoresis and Serum Protein Electrophoresis (SPEP).
Standardized automated workflow with excellent analytical performance.
Experienced pathologists and laboratory scientists.
Strict internal and external quality assurance programs.
Accurate, reliable, and clinically actionable reports.
